Product Informations

• Product No. BD-PM6069
• Synonyms Gastric mucin 6;Gastric Mucin;Gastric mucin-6;MUC 6;MUC-6;Muc6;MUC6 Fragment;MUC6 mucin;MUC6 mucin Fragment;MUC6_HUMAN;Mucin 6;Mucin 6 gastric;Mucin 6 oligomeric mucus/gel forming;Mucin glycoprotein Fragment;Mucin-6;Secretory mucin MUC6 Fragment
• Product Name Gastrin (6V7) Mouse Monoclonal Antibody
• Category 516
• Gene Name GAST GAS
• Protein Name Gastric mucin 6;Gastric Mucin;Gastric mucin-6;MUC 6;MUC-6;Muc6;MUC6 Fragment;MUC6 mucin;MUC6 mucin Fragment;MUC6_HUMAN;Mucin 6;Mucin 6 gastric;Mucin 6 oligomeric mucus/gel forming;Mucin glycoprotein Fragment;Mucin-6;Secretory mucin MUC6 Fragment
• Recommended Applications IHC-P,IF-P,IF-F,IF-ICC,ELISA
• Reactivity Human
• Preparation Method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Storage Buffer PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
• Specificity The antibody can specifically recognize human Gastrin protein.. The antibody was also Predict react with Mouse;Rat
• Dilution Ratio IHC-P 1:200-400. IF-P/IF-F/IF-ICC 1:50-200. ELISA 1:500-5000
• Predicted Molecular Weight 11kD
• Shipping and Storage Conditions -15°C to -25°C/1 year(Do not lower than -25°C)
• Cellular Localization Cytoplasmic
• Function function:Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.,online information:Gastrin entry,PTM:Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.,PTM:Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.,similarity:Belongs to the gastrin/cholecystokinin family.,
• Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Lead Time in stock
• Human Swissprot No. P01350
• Human Swissprot Link https://www.uniprot.org/uniprotkb/P01350/entry
• Mouse Swissprot No. P48757
• Rat Swissprot No. P04563

Picture

Human gastric adenocarcinoma tissue was stained with Anti-Gastrin Antibody

Product Details