Product Informations

• Product No. BD-PM6056
• Synonyms CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
• Product Name Cytokeratin 7 (7L9) Mouse Monoclonal Antibody
• Category 516
• Gene Name KRT7 SCL
• Protein Name CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7
• Recommended Applications IHC-P,ELISA
• Reactivity Human
• Preparation Method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Storage Buffer PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
• Specificity The antibody can specifically recognize human CK7 protein, and shows no cross reaction with CK1, 4, 5, 6, 8, 10, 14, 17, 18, 19, 20. In western blotting of Hela, A431, A549 and Hela cell lysates, the antibody can label a 51 kDa band corresponding to CK7 in A549 and Hela cell lysates.
• Dilution Ratio IHC-P 1:200-400. ELISA 1:500-5000
• Predicted Molecular Weight 52kD
• Shipping and Storage Conditions -15°C to -25°C/1 year(Do not lower than -25°C)
• Cellular Localization Cytoplasmic, Membranous
• Function function:Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).,induction:Up-regulated by retinoic acid.,mass spectrometry: PubMed:11840567,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,PTM:Arg-20 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. Interacts with eukaryotic translation initiator factor 3 (eIF3) subunit EIF3S10 and with HPV16 E7.,tissue specificity:Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver. Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus.,
• Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Lead Time in stock
• Human Swissprot No. P08729
• Human Swissprot Link https://www.uniprot.org/uniprotkb/P08729/entry
• Mouse Swissprot No. Q9DCV7
• Rat Swissprot No. Q6IG12

Picture

	Human kidney tissue was stained with Anti-Cytokeratin 7 Antibody
	Human liver tissue was stained with Anti-Cytokeratin 7 Antibody

Product Details