Product Informations

• Product No. BD-PM6043
• Synonyms 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2
• Product Name Cytokeratin 13 (3X9) Mouse Monoclonal Antibody
• Category 516
• Gene Name KRT13
• Protein Name 47 kDa cytokeratin;CK-13;CK13;Cytokeratin 13;Cytokeratin-13;K13;K1C13_HUMAN;Ka13;Keratin 13;Keratin;keratin type I cytoskeletal 13;Keratin-13;Krt-1.13;Krt1-13;KRT13;MGC161462;MGC3781;type I cytoskeletal 13;Type I keratin Ka13;WSN2
• Recommended Applications IHC-P,ELISA
• Reactivity Human
• Preparation Method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Storage Buffer PBS, pH7.2, 0.03% Porcolin 300, containing stabilizing protein
• Specificity The antibody can specifically recognize human CK13 protein. In western blotting of A431 cell lysate, the antibody can label a 50 kDa band corresponding to CK13.
• Dilution Ratio IHC-P 1:200-400. ELISA 1:500-5000
• Predicted Molecular Weight 50kD
• Shipping and Storage Conditions -15°C to -25°C/1 year(Do not lower than -25°C)
• Cellular Localization Cytoplasmic, Membranous
• Function disease:Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.,miscellaneous:There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).,online information:Keratin-13 entry,PTM:O-glycosylated; glycans consist of single N-acetylglucosamine residues.,similarity:Belongs to the intermediate filament family.,subunit:Heterotetramer of two type I and two type II keratins. keratin-13 is generally associated with keratin-4.,tissue specificity:Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.,
• Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
• Lead Time in stock
• Human Swissprot No. P13646
• Human Swissprot Link https://www.uniprot.org/uniprotkb/P13646/entry
• Mouse Swissprot No. P08730
• Rat Swissprot No. Q6IFV4

Picture

Human cervical squamous cell carcinoma tissue was stained with Anti-Cytokeratin 13 Antibody

Product Details