DKK3 Mouse Monoclonal Antibody

GoodsCode: BD-PA0010
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Specs Price Futures Quantity
  • 50μl
    200.00
    Three working days
    100μl
    350.00
    Three working days

Product Informations

  • Product No. BD-PA0010
  • Synonyms RIG; REIC
  • Product Name DKK3 Mouse Monoclonal Antibody
  • Category 493
  • Gene Name DKK3
  • Recommended Applications WB,FCM,Elisa
  • Reactivity Human,Monkey
  • Storage Buffer Ascitic fluid containing 0.03% New type preservative N.
  • Immunogen Purified recombinant fragment of human DKK3 expressed in E. Coli.
  • Dilution Ratio WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
  • Reference Molecular Weight 38kDa
  • Shipping and Storage Conditions 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
  • Host Mouse
  • Isotype IgG1
  • Clone No. 4G7
  • Lead Time Three working days
  • Clonality Monoclonal
  • Human Gene ID 27122

Picture

Western blot analysis using DKK3 mouse mAb against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate.
Flow cytometric analysis of MCF-7 cells using anti-DKK3 mAb (green) and negative control (purple).

Product Details

Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

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