Product Informations
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Product No.
BD-PA0010
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Synonyms
RIG; REIC
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Product Name
DKK3 Mouse Monoclonal Antibody
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Category
493
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Gene Name
DKK3
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Recommended Applications
WB,FCM,Elisa
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Reactivity
Human,Monkey
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Storage Buffer
Ascitic fluid containing 0.03% New type preservative N.
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Immunogen
Purified recombinant fragment of human DKK3 expressed in E. Coli.
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Dilution Ratio
WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
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Reference Molecular Weight
38kDa
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Shipping and Storage Conditions
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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Host
Mouse
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Isotype
IgG1
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Clone No.
4G7
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Lead Time
Three working days
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Clonality
Monoclonal
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Human Gene ID
27122
Picture
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Western blot analysis using DKK3 mouse mAb against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate. |
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Flow cytometric analysis of MCF-7 cells using anti-DKK3 mAb (green) and negative control (purple). |
Product Details
Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.