ZBTB7B Mouse Monoclonal Antibody

GoodsCode: BD-PA0011
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Specs Price Futures Quantity
  • 50μl
    200.00
    Three working days
    100μl
    350.00
    Three working days

Product Informations

  • Product No. BD-PA0011
  • Synonyms THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B
  • Product Name ZBTB7B Mouse Monoclonal Antibody
  • Category 493
  • Gene Name ZBTB7B
  • Recommended Applications WB,IHC-P,ICC,Elisa
  • Reactivity Human
  • Storage Buffer Ascitic fluid containing 0.03% New type preservative N.
  • Immunogen Purified recombinant fragment of human ZBTB7B expressed in E. Coli.
  • Dilution Ratio WB 1:500-1:2000, IHC-P 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:10000
  • Reference Molecular Weight 58kDa
  • Shipping and Storage Conditions 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
  • Host Mouse
  • Isotype IgG1
  • Clone No. 7C12
  • Lead Time Three working days
  • Clonality Monoclonal
  • Human Gene ID 51043

Picture

Western blot analysis using ZBTB7B mAb against HEK293 (1,2) cell lysate.
Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin
Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B mouse mAb

Product Details

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

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