Product Informations
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Product No.
BD-PA0007
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Synonyms
NR3C4; KD; AIS; SMAX1; HUMARA; AR
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Product Name
Androgen receptor Mouse Monoclonal Antibody
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Category
493
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Gene Name
AR
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Recommended Applications
WB,IHC-P,Elisa
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Reactivity
Human
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Storage Buffer
Ascitic fluid containing 0.03% New type preservative N.
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Immunogen
Purified recombinant fragment of human AR expressed in E. Coli.
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Dilution Ratio
WB 1:500-1:2000, IHC-P 1:200-1:1000, ELISA 1:10000
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Reference Molecular Weight
110kDa
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Shipping and Storage Conditions
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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Host
Mouse
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Isotype
IgG1
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Clone No.
2H8
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Lead Time
Three working days
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Clonality
Monoclonal
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Human Gene ID
367
Picture
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Western blot analysis using Androgen receptor mouse mAb against K562 (1), Jurkat (2) and LNCaP (3) cell lysate. |
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Immunohistochemical analysis of paraffin-embedded human Prostate tissues using Androgen receptor mouse mAb |
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Immunohistochemical analysis of paraffin-embedded human testis (left) and prostate cancer (right) tissues using Androgen Receptor mouse mAb with DAB staining. |
Product Details
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
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