Product Informations
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Product No.
BD-PA0017
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Synonyms
T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247
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Product Name
CD247 Mouse Monoclonal Antibody
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Category
493
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Gene Name
CD247
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Recommended Applications
IHC-P,ICC,FCM,Elisa
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Reactivity
Human
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Storage Buffer
Ascitic fluid containing 0.03% New type preservative N.
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Immunogen
Purified recombinant fragment of human CD247 expressed in E. Coli.
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Dilution Ratio
IHC-P 1:200-1:1000, ICC 1:200-1:1000, FCM 1:200-1:400, ELISA 1:10000
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Reference Molecular Weight
18kDa
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Shipping and Storage Conditions
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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Host
Mouse
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Isotype
IgG1
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Clone No.
4B10
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Lead Time
Three working days
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Clonality
Monoclonal
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Human Gene ID
919
Picture
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Figure3: Immunofluorescence analysis of K562 cells using anti-CD247 mAb (green). Blue: DRAQ5 fluorescent DNA dye. |
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Flow cytometric analysis of Jurkat cells using anti-CD247 mAb (green) and negative control (purple). |
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Immunohistochemical analysis of paraffin-embedded human Thymus tissues using anti-CD247 mouse mAb |
Product Details
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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