Product Informations
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Product No.
BD-PA0013
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Synonyms
KRT7; cytokeratin 7
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Product Name
CK7 Mouse Monoclonal Antibody
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Category
493
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Gene Name
CK7
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Recommended Applications
WB,FCM,Elisa
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Reactivity
Human
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Storage Buffer
Ascitic fluid containing 0.03% New type preservative N.
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Immunogen
Purified recombinant fragment of human CK7 expressed in E. Coli.
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Dilution Ratio
WB 1:500-1:2000, FCM 1:200-1:400, ELISA 1:10000
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Reference Molecular Weight
51kDa
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Shipping and Storage Conditions
4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
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Host
Mouse
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Isotype
IgG1
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Clone No.
5D12
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Lead Time
Three working days
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Clonality
Monoclonal
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Human Gene ID
3855
Picture
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Western blot analysis using CK7 mouse mAb against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate. |
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Flow cytometric analysis of Hela cells using anti-CK7 mAb (green) and negative control (purple). |
Product Details
CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
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