Recombinant Human CD16 Monoclonal Antibody

GoodsCode: BDAA0257
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Specs Price Futures Quantity
  • 500μg
    380.00
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    10mg
    6720.00
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    25mg
    14710.00
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Product Informations

  • Product No. BDAA0257
  • Product Name Recombinant Human CD16 Monoclonal Antibody
  • Purity >90%,采用 SDS-PAGE 凝胶及 HPLC 分析
  • Category 400
  • Concentration 推荐使用浓度:500ng/mL
  • Appearance 无色透明液体
  • Shipping and Storage Conditions 冰袋运输;-20℃保存,有效期为24个月(未开盖);开盖后建议分装保存,开盖后-20℃保存期6个月,-80℃保存期1个月,避免反复冻融。
  • Expression System HEK293细胞
  • Background CD16即FcγRⅢ,为分子量为50,000~70,000Da的糖蛋白,属Ig超家族成员。CD16分子广泛表达于NK细胞、嗜中性多形核白细胞、单个核细胞和巨噬细胞中。CD16是IgG的低亲和力受体,与CD3ζ的Fcε关联受体I(Fc 的εRI)γ链结合,共同参与信号转导。CD16抗体可以通过与NK细胞表面的CD16结合,介导NK细胞杀死IgG1或IgG3抗体靶向的细胞,共同参与人NK细胞的直接杀伤过程。CD16抗体促进NK细胞的增殖和杀伤性细胞因子的分泌,激活NK细胞抗体依赖性细胞介导的细胞毒性(ADCC)作用,增强NK细胞对肿瘤细胞的识别和清除能力。
  • Purification ProteinA 亲和层析并精纯

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